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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCA2
All Species:
15.45
Human Site:
Y1216
Identified Species:
28.33
UniProt:
Q9BZC7
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BZC7
NP_001597
2435
269873
Y1216
K
G
T
Y
G
D
G
Y
R
L
T
L
V
K
R
Chimpanzee
Pan troglodytes
XP_001152577
2346
264166
A1153
A
I
A
F
V
G
D
A
K
V
V
I
L
D
E
Rhesus Macaque
Macaca mulatta
XP_001117819
2476
273629
Y1243
K
G
T
Y
G
D
G
Y
R
L
T
L
V
K
R
Dog
Lupus familis
XP_537788
2395
264756
H1206
E
Q
S
L
D
T
L
H
L
S
S
F
G
L
M
Cat
Felis silvestris
Mouse
Mus musculus
P41234
2434
270490
Y1216
K
G
A
Y
G
D
G
Y
R
L
T
L
V
K
Q
Rat
Rattus norvegicus
Q9ESR9
2434
270910
Y1216
K
G
A
Y
G
D
G
Y
R
L
T
L
V
K
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516009
2266
254238
C1115
I
S
H
G
K
L
C
C
V
G
S
S
L
F
L
Chicken
Gallus gallus
XP_422330
2276
256293
L1125
H
M
D
E
A
D
I
L
G
D
R
I
A
I
I
Frog
Xenopus laevis
NP_001089022
2363
267334
Y1163
P
T
S
G
V
D
P
Y
S
R
R
S
I
W
D
Zebra Danio
Brachydanio rerio
NP_001139161
2268
254351
S1117
G
K
L
C
C
V
G
S
S
L
F
L
K
T
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34358
1704
191394
K553
I
I
V
R
N
L
V
K
I
W
S
T
T
G
E
Sea Urchin
Strong. purpuratus
XP_798273
1913
213253
Q762
C
L
N
L
Y
E
G
Q
I
T
S
F
L
G
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84M24
1882
209045
K730
W
Q
L
I
K
K
I
K
K
G
R
I
I
L
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
35.1
96
82.2
N.A.
91
92.9
N.A.
39.1
35.7
36.5
37.7
N.A.
N.A.
N.A.
23.7
41.7
Protein Similarity:
100
52
96.6
86.1
N.A.
93.2
94.9
N.A.
55.7
53.5
54.7
54.5
N.A.
N.A.
N.A.
39
54.4
P-Site Identity:
100
0
100
0
N.A.
86.6
93.3
N.A.
0
6.6
13.3
20
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
100
33.3
100
26.6
N.A.
93.3
93.3
N.A.
13.3
13.3
26.6
26.6
N.A.
N.A.
N.A.
6.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
42.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
24
0
8
0
0
8
0
0
0
0
8
0
0
% A
% Cys:
8
0
0
8
8
0
8
8
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
8
47
8
0
0
8
0
0
0
8
8
% D
% Glu:
8
0
0
8
0
8
0
0
0
0
0
0
0
0
16
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
8
16
0
8
0
% F
% Gly:
8
31
0
16
31
8
47
0
8
16
0
0
8
16
0
% G
% His:
8
0
8
0
0
0
0
8
0
0
0
0
0
0
8
% H
% Ile:
16
16
0
8
0
0
16
0
16
0
0
24
16
8
8
% I
% Lys:
31
8
0
0
16
8
0
16
16
0
0
0
8
31
0
% K
% Leu:
0
8
16
16
0
16
8
8
8
39
0
39
24
16
16
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
8
0
8
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
8
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% P
% Gln:
0
16
0
0
0
0
0
8
0
0
0
0
0
0
16
% Q
% Arg:
0
0
0
8
0
0
0
0
31
8
24
0
0
0
24
% R
% Ser:
0
8
16
0
0
0
0
8
16
8
31
16
0
0
0
% S
% Thr:
0
8
16
0
0
8
0
0
0
8
31
8
8
8
0
% T
% Val:
0
0
8
0
16
8
8
0
8
8
8
0
31
0
0
% V
% Trp:
8
0
0
0
0
0
0
0
0
8
0
0
0
8
0
% W
% Tyr:
0
0
0
31
8
0
0
39
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _